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| 贞冰口溃宁含片抗炎镇痛促进溃疡愈合药效学研究 |
| Anti inflammation, Analgesia and Ulcer Healing Promotion of Zhenbing Koukuining Tablets |
| 投稿时间：2014-09-19 修订日期：2014-12-28 |
| DOI： |
| 中文关键词: 贞冰口溃宁含片 抗炎 镇痛 促进溃疡愈合 |
| 英文关键词:Zhenbing Koukuining tablets Anti inflammation Analgesia Ulcer healing promotion |
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| 中文摘要: |
| 摘 要 目的： 研究贞冰口溃宁含片抗炎镇痛促进溃疡愈合的作用。方法: 采用巴豆油致小鼠耳廓肿胀法观察其抗炎作用，醋酸致小鼠扭体法观察其镇痛作用，醋酸致金黄地鼠口腔溃疡法观察其促进溃疡愈合的作用。结果:贞冰口溃宁含片能明显减轻小鼠耳廓肿胀度（P<0.01）；减少小鼠扭体次数（P<0.05）；显著缩小溃疡直径（P<0.01或P<0.05），减轻炎症反应。结论: 贞冰口溃宁含片具有抗炎、镇痛、促进溃疡愈合的作用。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the anti inflammation, analgesia and ulcer healing promotion of Zhenbing Koukuining tablets. Methods: The anti inflammatin, analgesia and ulcer healing promotion of the preparation was respectively observed in the croton oil induced auricular edema in mice, acetic acid induced writhing in mice and acetic acid induced oral ulcer in golden hamsters. Results: The tablets could obviously alleviate the auricular edema（P<0.01） and reduce the writhing times in mice（P<0.05）, and narrow the oral ulcer（P<0.01 or P<0.05） and inhibit the inflammation reaction in golden hamsters. Conclusion:Zhenbing Koukuining tablets have anti inflammatory, analgesia and ulcer healing promotion effects. |
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