ABSTRACT Objective:To survey the patients with hyperalgesia situation after remifentanil anesthesia in operation.Methods:200 cases of patients who did remifentanil anesthesia surgery from January 2007 to December 2012 were selected as the research objects in our hospital, set as experimental group. 195 patients of fentanyl anesthesia surgery were selected as control group. The difference of VAS pain score and mechanical pain treshald of patients between two groups and evaluated patients with mechanical pain threshold were observed.Results: VAS pain score of patients during preoperative between two groups had no significant difference (P>0.05).VAS pain score of experimental group within 90 min after anesthesia awake at different times increase apparently, differences were statistically significant(P<0.01), and was lower than that of control group at the same period, differences were statistically significant(P< 0.05).Patients of two groups with preoperative mechanical pain threshold had no statistical difference (P>0.05), after anesthesia awake, mechanical pain threshold of experimental group within 90 min in different time points compared with preoperative significantly reduced, differences were statistically significant (P<0.01), and was higher than that of control group at the same period, differences were statistically significant (P<0.05). Conclusion: Remifentanil anesthesia with fentanyl after hyperalgesia had higher pain after anaesthesia and mechanical pain threshold was low. When used remifentanil, intervene therapy measures should be taken to relief pain. |