国家科技部中国科技论文统计源期刊   中国科技核心期刊   WHO西太平洋地区医学索引(WPRIM)收录期刊   湖北优秀期刊
《药物流行病学杂志》官方网站与投审稿系统变更通知<点击查看详情>
丹红注射液辅助治疗冠心病心绞痛疗效观察
Clinical Efficacy of Adjuvant Therapy with Danhong Injections in Angina Pectoris
投稿时间:2014-09-28  修订日期:2015-01-17
DOI:
中文关键词:  冠心病心绞痛  丹红注射液  疗效  安全性
英文关键词:Angina pectoris  Danhong injections  Efficacy  Safety
基金项目:
作者单位
王桂萍 云和县中医医院药剂科 浙江云和 323600 
方伟钧 浙江省丽水市中心医院急诊科 
潘锋君 浙江省丽水市中心医院药剂科 
摘要点击次数: 848
全文下载次数: 0
中文摘要:
      摘 要 目的: 探讨冠心病心绞痛采用丹红注射液治疗的临床疗效及安全性。方法: 120例冠心病心绞痛患者随机均分为观察组和对照组。对照组患者给予吸氧、抗感染、祛痰及平喘等常规治疗,观察组在对照组基础上加用丹红注射液30 ml+5%葡萄糖注射液250 ml,ivd,qd。两组疗程均为2周。比较两组治疗前后的血液流变学及血脂变化情况,评价两组治疗后的心电图和临床症状改善的疗效。结果:治疗后,两组患者的血液流变学指标均较前明显降低(P<0.01),且观察组患者改善效果明显优于对照组(P<0.01)。两组患者的TC、TG、LDL均较前明显降低(P<0.01),HDL较前明显升高(P<0.01),且观察组各项指标较治疗前的改善效果明显优于对照组(P<0.01)。观察组临床症状改善与心电图改善总有效率均明显高于对照组(P<0.05)。结论: 丹红注射液治疗冠心病心绞痛,可显著改善患者的血液流变学和血脂状况,提高治疗的临床疗效,值得广泛推广应用。
英文摘要:
      ABSTRACT Objective: To evaluate the clinical efficacy and safety of Danhong injections in the adjuvant therapy for angina pectoris. Methods: According to a random number table, totally 120 cases of patients with angina pectoris were randomly divided into the observation group and the control group. The control group was treated with the conventional therapy, such as oxygen uptake, anti inflammation, expectoration and relieving asthma, and the observation group was treated with Danhong injections (30ml added in 250ml glucose infusions, ivd, qd) additionally. The treatment course was 2 weeks. The hemorheology and blood lipid changes before and after the treatment were recorded, the ECG was analyzed and the clinical symptom improvement was evaluated in the two groups.Results: After the treatment, the hemorheological indices of the two groups were significantly reduced (P<0.01), and the improvement of the observation group was much better than that of the control group (P<0.01). After the treatment, the TC, TG and LDL were significantly lower and the HDL was notably higher than those before the treatment in the two groups(P<0.01), and the improvement of the observation group was significantly better than that in the control group(P<0.01). The total efficiency of ECG and clinical symptom improvement in the observation group was significantly higher than that in the control group (P<0.05). Conclusion:Danhong injections in the treatment of angina pectoris can significantly improve the hemorheology and blood lipid to enhance the clinical efficacy, which are worthy of promoted application.
查看全文  查看/发表评论  下载PDF阅读器
关闭