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110例癫癎患儿丙戊酸钠血药浓度监测 |
Monitoring of Blood Concentration of Sodium Valproate in 110 Cases of Ill Children with Epilepsy |
修订日期:2002-06-19 |
DOI: |
中文关键词: 丙戊酸钠 血药浓度 荧光偏振免疫法 |
英文关键词:Sodium valproate,Blood concentration,FPIA |
基金项目: |
杨彤 |
Yang Tong Department of Pharmacy,Guangzhou City Children's Hospital,510200,P.R.China |
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中文摘要: |
110例癫癎患儿丙戊酸钠血药浓度监测@杨彤~~~~ |
英文摘要: |
Objective: To analyse the monitoring result of sodium valproate used for patients with epilepsy. Method: Fluorescence polarization immunoassay(FPIA) was used. Result: Of the monitoring results of blood concentration in 110 cases of ill children diagnosed as epilepsy, the blood concentrations were within therapeutical range in 47.27% of patients, that were less than the range in 37.27%, that were higher than the range in 15.45%. Conclusion: The individual difference of blood concentration was large in ill children with epilepsy after taking sodium valproate, timely monitoring of blood concentration and conduct of individual administration have a important significance for controlling seizure. |
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