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吲哚美辛栓对增强吗啡术后镇痛的疗效观察
Observation of Curative Effects of Morphine Postoperative Analgesia Enhanced by Indomethacin Suppository
  
DOI:
中文关键词:  吲哚美辛栓 吗啡 术后 镇痛 疗效 硬膜外止痛 生理盐水 麻醉药
英文关键词:Indomethacin suppository,Morphine,Extradual acesodyne
基金项目:
吴艳琴  黄贤明  许宗娒
温州市第三人民医院麻醉科 浙江温州325000 (吴艳琴,黄贤明)
,温州市第三人民医院麻醉科 浙江温州325000(许宗妃)
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中文摘要:
      目的:探讨术前预用吲哚美辛栓对吗啡硬膜外止痛效果的影响。方法:选择择期妇科手术患者120例,随机分为3组,每组40例,术半3组患者均从硬膜外导管注入吗啡2.0吨(用生理盐水稀释至10mL)。A组为对照组。B组在硬膜外操作完成,注入麻醉药前经直肠给吲哚美辛栓100吨,C组在术后8h经直肠给吲哚美辛栓100吨,手术后8,12,24,36h观察镇痛效果。结果:术后VAS评分8h时B组低于A、C组(P<0.05),术后12h后A组评分明显高于B、C组(P<0.05),B组低于C组(P<0.05)。结论:吲哚美辛栓能增强吗啡硬膜外止痛效果.术前预用效果更好。
英文摘要:
      Objective: To discuss the effects of morphine extradural acesodyne through pre using indomethacin suppository before operation.Method: 120 patients were chosen for gynaecologic operation and divided into 3 groups at random with 40 patients each group. After operation,2.0mg morphine (diluted to 10ml by physiological saline) was injected into these patients by extradual vessels. Group A was made a compared one, and Group B received a transfusion of 100mg indomethacin suppository through rectum after finishing the extradual operation and before injecting anaesthetic; Group C received a transfusion of 100mg indomethacin suppository through rectum 8h later. Then we observed their analgesia effects 8 h, 12 h, 24 h and 36 h later respectively.Result: It was found that Group B's VAS mark was lower than Group A's and Group C's at 8h after operation ( P < 0.05 ); however, 12 h later Group A's mark was obviously higher than Group B's and Group C's ( P < 0.05 ) and Group B's was lower than Group C's.Conclusion: It is clear that indomethacin suppository can enhance the effect of morpine extradual acesodyne.
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