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| 含利福喷丁方案对结素强阳性患者预防性治疗效果观察 |
| A Study of Treatment Effects of Rifapentine Preventing Teenager Tuberculosis against Positive PPD Reaction |
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| DOI： |
| 中文关键词: 利福喷丁 预防性治疗 结核病 结核菌素强阳性 药物不良反应 抗结核杆菌活性药物 |
| 英文关键词:Rifapentine,Tuberculosis,Prevention |
| 基金项目: |
| 高三友 王友谊 何家荣 |
| [1]河南省结核病防治研究所郑州450003 [2]阿南省商丘市结核病防治所 [3]河南省信阳市结核病防治所 |
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| 中文摘要: |
| 目的：探讨含利福喷丁方案对结核菌素强阳性患者预防性治疗的依从性及治疗效果。方法：追踪观察结核菌素强阳性患者的利福喷丁预防性治疗过程，了解方案的依从情况及结核病发病情况。结果：5468例结核病高危患者，预防性治疗接受率83．87％，药物不良反应发生率7．20％。活动性结核病5年发病率404．968／10万，低于一般人群。结论：含利福喷丁的预防性治疗方案，对结核病的发生具有较好的预防作用，且依从性良好。 |
| 英文摘要: |
| Objective: To reveal the treatment effects of rifapentine preventing teenager tuberculosis.Method: The course of the preventative treatment of rifapentine against the positive PPD reaction was continually observed and an acceptable scheme and incidence of teenager tuberculosis were studied.Result: The acceptable rate was 83.87% . The rate of adverse drug reactions was 7.20% . The active tuberculosis incidence was 404.968 /106 during five years. It was lower than that in general mass.Conclusion: It was feasible that patients with the positive PPD reaction were treated for three months with the plan consisting of rifapentine preventing tuberculosis. |
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