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利培酮与氯丙嗪治疗精神分裂症对心电图的影响
The Effects of the Treatment of Patients with Risperidone and Chlorpromazine on Electrocardiogram(ECG)
  
DOI:
中文关键词:  利培酮 氯丙嗪 药物治疗 精神分裂症 心电图 药物不良反应
英文关键词:Risperidone,Chlorpromazine,ECG,Adverse drug reaction
基金项目:
董秀凤  张玉胜  吴丽荣
滨州市人民医院 山东滨州256610 (董秀凤,张玉胜)
,滨州市人民医院 山东滨州256610(吴丽荣)
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中文摘要:
      目的 :了解和比较利培酮与氯丙嗪对心电图的影响。方法 :对服用利培酮及氯丙嗪的精神分裂症患者分别定期心电图检查 ,时间为服药后 2、4周。结果 :利培酮组和氯丙嗪组出现异常分别为 11.5 %和 4 2 .5 % ,两者有显著性差异 (P <0 .0 5 )。结论 :利培酮对心电图影响明显低于氯丙嗪。
英文摘要:
      Objective: To study the effect of the treatment of patients with risperidone and chlorpromazine on ECG respectively. Methods: The patients were treated with risperidone and chlorpromazine, and ECG were regularly recorded in 2 to 4 weeks separately. Result: The abnormal rate was 11.5% in the risperidone group and that of chlorpromazine, 42.5% . The significant differences were found between the two groups ( P < 0.05 ). Conclusion: The effect of risperidone on the abnormal ECG was lower than that of chlorpromazine.
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