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冻干治疗用母牛分枝杆菌菌苗治疗慢性乙型肝炎疗效分析
An Analysis of Curative Effect in Treating the Chronic Hepatitis B with the Freeze-dried M. vaccae Vaccine for Therapy
投稿时间:2004-10-26  
DOI:
中文关键词:  母牛分枝杆菌菌苗(微卡)/冻干治疗 乙型肝炎,慢性 乙肝病毒核糖核酸 乙肝e抗原
英文关键词:Freeze-dried M. vaccae vaccine for therapy (Vaccae,),CHB(chronie hepatitis B),HBV-DNA,HBeAg
基金项目:韶关市医药卫生科研资助项目(Y04067)
吴英梅  雷卫平  符惠燕
[1]粤北第二人民医院,广东韶关512026 [2]广州中医药大学,广东韶关512026
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中文摘要:
      目的:观察冻干治疗用母牛分枝杆菌菌苗(微卡)治疗慢性乙型肝炎(CHB)中的有效性和安全性。方法:CHB60例分成2组。治疗组:33例,主要用药为母牛分枝杆菌菌苗(微卡)+乙肝疫苗+双嘧达莫。对照组:27例,常规保肝治疗,主要用药为肌苷+葡糖醛酸+维生素C。6个月为1个疗程。结果:治疗组HBV-DNA、HBeAg阴转12例(36.36%),无不良反应。两组比较差异有显著性(P〈0.05)。结论:冻干治疗用母牛分枝杆菌菌苗治疗CHB安全有效,无不良反应。
英文摘要:
      Objective:To observe the effect and safety of the freeze - dried M. vaccae vaccine for therapy ( Vaccae ) in treating the CHB (chronic hepatitis B) . Method: 60 cases of CHB were divided into two groups. In the treatment group with 33 cases, the major medicines were freeze - dried M. vaccae vaccine for therapy, HBB and dipyridamole. In the control group with 27 cases, a regular treatment was offered to protect the liver. The major medicines are glucurone, inosi-num and vitamin C. One treatment course was 6 months. Result:In the treatment group, HBV-DNA and HBeAg of 12 cases (36.36%) improved without ADR(Adverse Drug Reaction) curative effects. The difference of the two groups obvious (P < 0. 05 ). Conclusion:Treating CHB with the freeze - dried M. vaccae vaccine for therapy is safe and effective without any ADR.
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