| Objective: To compare the effect and cost of 3 therapeutic schemes of triple therapy in eradication of helicobacter pylori(Hp). Method:86 cases who were diagnosed as gastric ulcer or duodenal ulcer by gastroscope with Hp positive were divided into three groups. The RCF7 group received rabeprazole(R) 10 mg + clarithromycin(C)0. 5 +fura-zolidone(F) 0. 2, bid,for 7 d, and the RAC7 group or the RAC5 group was provided with RIO mg + amoxicilin(A) 1.0 + C 0.5,bid, for 7 d or 5 d, respectively. The three groups were provided with RIO mg, qd after the combination treatment was finished. The period of the treatment persisted 3 weeks. The data were evaluated by using the cost minimization analysis of pharmacoeconomic. Result:There was no statistically significant difference for the Hp eradication rates and the ulcer healing rates of the three groups( P > 0. 05 ) , but the costs of the therapeutic schemes were different. Conclusion:The costs showed that the RAC5 group's cost was the least, and therefore suitable for patients. |
