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破伤风抗毒素致过敏性休克68例文献分析
Analysis of 68 Cases of Tetanus Antitoxin-induced Allergic Shock
投稿时间:2005-04-20  修订日期:2005-10-10
DOI:
中文关键词:  破伤风抗毒素  药物不良反应  过敏性休克  文献分析
英文关键词:Tetanus antitoxin,Allergic Shock,Adverse drug reaction (ADR),Analysis of literature
基金项目:
王川平  王昕  孙莉
河北医科大学第二医院药剂科,石家庄050000
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中文摘要:
      目的:探讨破伤风抗毒素致过敏性休克的特点和规律。方法:检索中文医药卫生期刊1994年-2004年12月报道的破伤风抗毒素致过敏性休克个案,并进行统计分析。结果:破伤风抗毒素致过敏性休克,主要发生在用药后30min以内。男性多于女性。结论:用药前应询问过敏史,严格用药指征,观察用药后反应,方能确保用药安全。
英文摘要:
      Objective:To probe into the characteristics and regularities of Tetanus antitoxin - induced allergic shock. Method:The case reports of Tetanus antitoxin-induced allergic shock published in Chinese medical periodicals during the period of 1994 to 2004 were collected and analyzed. Result:The tetanus antitoxin - induced allergic shock occurred mostly within 30 minutes, and the male cases outnumbered the female cases. Conclusion:Allergic history should be taken in detail before the use; the indications of drug use, strictly controlled and the ADRs, observed so as to ensure the safe use of drugs.
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