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| 婴幼儿抗生素相关性腹泻临床分析 |
| Clinical Analysis of Antibiotic-related Diarrhea in Infants |
| 投稿时间：2006-04-14 修订日期：2006-06-09 |
| DOI： |
| 中文关键词: 头孢硫脒 头孢呋辛 婴幼儿 抗生素相关性腹泻病 微生态制剂 |
| 英文关键词:Cefathiamidine Cefuroxime Antibiotic-related diarrhea Ecosystem protectant agent |
| 基金项目: |
| 梅忠卓 |
| 长春市儿童医院 长春130061 |
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| 中文摘要: |
| 目的：提高对头孢茵素在应用过程中导致婴幼儿抗生素相关性腹泻的认识,并探讨其防治方法。方法：随机选择呼吸道感染婴幼儿,分别应用头孢硫脒治疗200例,头孢呋辛188例,每日应用量均为50～100mg·kg·d~(-1),分两次静滴,疗程7～14 d,观察两组抗生素相关性腹泻发生率,进行统计学分析,探讨其发病原因,及防治办法。结果：两组婴幼儿抗生素相关性腹泻发病率分别为14%、22．3%,应用微生态制剂及肠粘膜保护药治疗腹泻,均取得满意疗效。结论：婴幼儿抗生素相关性腹泻发病率较高,与多种因素有关,可应用微生态制剂及肠粘膜保护药防治抗生素相关性腹泻。 |
| 英文摘要: |
| Objective:To enhance the recognition of antibiotic-related diarrhea in infants and study the method of prevention and treatment.Method:382 infants with respiratory tract infections were chosen by random.200 cases of respir- atory tract infections were treated with cefathiamidine,and 182 cases,with cefuroxime,(500-1 000 mg with per kilo body weight,drop twice a day) for 7-14 days.The incidence rate of antibiotic-associated diarrhea was observed,and its statisti- cal analysis,made,the cause of morbidity,investigated,and the therapeutic efficacy,evvaluated.Result:The incidence rates of antibiotic-related diarrhea in the two groups were 14% and 20.9% respectively.The curative effect of diarrhea treated with ecosystem and bowel mueosa protective agents was satisfactory.Conclusion:The incidence rate of the antibiot- ic-related diarrhea in infants was high and was related with many factors.The ecosystem and bowel mucosa protective agents may prevent and cure the antibiotic-related diarrhea. |
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