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| 骨科无菌手术预防应用抗菌药的成本-效果分析 |
| Cost-effectiveness Analysis of Common Antibiotics for Prevention of Post-operation Infections in Orthopedic Aseptic Operations |
| 投稿时间：2006-06-19 修订日期：2006-11-20 |
| DOI： |
| 中文关键词: 抗菌药 骨科 无菌手术 I类伤口 成本-效果分析 |
| 英文关键词:Antibiotics,Orthopedic surgery,Aseptic operation,Analogous wound,Cost-effectiveness analysis |
| 基金项目: |
| 孙惠娟 孙艳 陈柏清 李艳华 |
| 解放军总医院药品保障中心药库 北京100853 |
| 摘要点击次数: 1187 |
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| 中文摘要: |
| 目的:探讨骨科无菌手术应用5种常用抗菌药预防感染的经济效果。方法:随机抽取2006年1～3月的骨科无菌手术135例,Ⅰ类伤口,术前无感染指征,统计病例一般资料和抗菌药使用情况,对5种常用抗菌药预防骨科手术感染进行回顾性分析,比较5种常用抗菌药预防手术感染的成本-效果。结果:在调查的5种药物中,头孢呋辛钠是预防骨科无菌手术感染的最佳用药选择。结论:开展成本-效果分析有助于合理用药,控制用药成本。 |
| 英文摘要: |
| Objective:To evaluate the economic effectiveness of five antibiotics for prevention of post-operation infections in orthopedic aseptic operations.Method:According to the application of five commonly-used antibiotics to 135 cases of orthopedic aseptic operations,which were analogous wounds and had no infectious signs before surgery,a cost-ef- fectiveness analysis was comparatively made by using the principle of pharmacoeconomics for the five antibiotics for preven- tion of post-operation infections.Result:In the principles of the pharmacoeconomics,cefuroxime sodium was the best anti- biotic to prevent the infection of orthopedic aseptic operations.Conclusion:The cost-effectiveness analysis is very helpful to choose the best rational therapeutic regime and to gain the maximal therapeutic effectiveness with a minimal cost. |
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