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375位医务人员接种甲流疫苗不良反应分析
Analysis of the Safety of 375 H1N1 Influenza Vaccine Inoculators
投稿时间:2010-12-02  修订日期:2011-03-08
DOI:
中文关键词:  甲型H1N1流感裂解疫苗  药品不良反应  安全性
英文关键词:H1N1 influenza A vaccine  Adverse drug reaction  Safety
基金项目:
作者单位
李金兰 南华大学药物药理研究所( 湖南衡阳 421001) 
黄红林 南华大学药物药理研究所( 湖南衡阳 421001) 
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中文摘要:
      摘 要 目的:了解医务人员接种甲型H1N1流感裂解疫苗的不良反应(ADR)发生情况。方法:观察该医院375名医务工作者接种甲型H1N1流感裂解疫苗后的ADR,统计分析ADR发生率、出现时间、持续时间、转归等。结果:375例甲型H1N1流感裂解疫苗接种者中发生ADR10例,发生率2.7%。均为一般ADR,所有的ADR经对症治疗后均可治愈。结论:甲型H1N1流感裂解疫苗总体ADR以轻度ADR为主,均可治愈,疫苗的安全性较好。
英文摘要:
      ABSTRACT Objective:To probe into the incidence rate of ADR and safety of H1N1 influenza A vaccine.Method:375 medical workers inoculated with influenza A (H1N1) vaccines were included in this study. The incidence, occurrence time, duration and outcome of their adverse reactions were observed.Result:The total incidence of adverse reactions in 375 vaccinated people was 2.7% (10 of 375). All the adverse reactions were able to heal spontaneously or were cured.Conclusion:H1N1 influenza A vaccine caused mild adverse drug reactions in a few subjects, and the symptoms could be quickly recovered spontaneously. The vaccine is relatively safe.
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