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| 2006～2010年住院患者抗菌药使用强度分析 |
| Analysis of Antibacterial Use Density in a Hospital from 2006 to 2010 |
| 投稿时间：2011-01-14 修订日期：2011-04-01 |
| DOI： |
| 中文关键词: 抗菌药 使用强度 用药分析 |
| 英文关键词:Antibacterials Antibacterial use density Drug analysis |
| 基金项目: |
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| 中文摘要: |
| 摘 要 目的：分析某医院住院患者抗菌药使用情况，为合理使用抗菌药提供参考依据。方法：收集该院2006～2010年住院患者抗菌药使用记录，以限定日剂量(DDD) 为单位，计算抗菌药使用强度(AUD) 并进行分析。结果：该院住院患者AUD 5 年间波动不大，头孢菌素类、β 内酰胺酶抑制药复合制剂和青霉素类排名AUD前3 位；排名AUD 前10 位的药品大部分来自于头孢菌素类、β-内酰胺酶抑制药复合制剂、硝咪唑类和喹诺酮类。结论：该院可能存在用药集中、广谱抗菌药的使用率高等问题；应严格限制头孢菌素类、β-内酰胺酶抑制药复合制剂和喹诺酮类的临床应用，避免AUD 的过快增长。 |
| 英文摘要: |
| ABSTRACT Objective:To analyze the antibacterial use in a hospital to provide an evidence for rational use of antibacterials. Method:With defined daily dose (DDD) as the unit, the data of drugs used in a hospital from 2006 to 2010 were collected to calculate and analyze the antibacterial use density (AUD). Result:The AUD was fluctuant during the last 5 years. Cephalosporins, beta-lactamase/inhibitors and penicillins ranked in the first three places. The drugs ranking in the first ten places came from cephalosporins, beta lactamase/inhibitors, nit romidazoles and fluoroquinolones. The majority of antibacterials were injections.Conclusion:The hospital may have such problems as dense medication, frequent use of broad-spectrum antimicrobial agents. Cephalosporins, beta-lactamase/inhibitors and fluoroquinolones should be strictly limited in the clinic to avoid an excessive increase in AUD. |
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