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| 布地奈德福莫特罗用于慢阻肺急性加重期观察 |
| Observation of Budesonide and Formoterol Fumarate Powder for Inhalation in the Treatment of Acute Exacerbations of Chronic Obstructive Pulmonary Disease |
| 投稿时间：2011-03-23 修订日期：2011-05-31 |
| DOI： |
| 中文关键词: 慢性阻塞性肺疾病 急性加重期 布地奈德福莫特罗粉吸入剂 |
| 英文关键词:Acute exacerbations of chronic obstructive pulmonary disease Budesonide and formoterol fumarate powder for inhalation |
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| 中文摘要: |
| 摘 要 目的：观察布地奈德福莫特罗粉吸入剂治疗慢性阻塞性肺疾病急性加重期（AECOPD）的临床疗效和安全性。方法：80例AECOPD患者随机分为观察组和对照组各40例，两组均采用常规治疗，观察组加用布地奈德福莫特罗粉吸入剂，比较两组临床疗效、症状明显缓解时间、不良反应。结果： 观察组总有效率95.0%，对照组总有效率80.0%，观察组疗效优于对照组（P＜0.05），观察组咳嗽、咳痰、气喘症状明显缓解时间较对照组显著缩短（P＜0.05）；两组均未见明显不良反应。结论：布地奈德福莫特罗粉吸入剂治疗AECOPD疗效确切，安全性好。 |
| 英文摘要: |
| ABSTRACT Objective:To observe the clinical efficacy and security of budesonide and formoterol fumarate powder for inhalation（symbicort turbuhaler）in the treatment of acute exacerbations of chronic obstructive pulmonary disease （AECOPD）． Method:0 cases of AECOPD were randomly divided into the observation group and controlled group with 40 cases of each group．Both groups received the conventional treatment．The observation group were additionally treated with budesonide and formoterol fumarate powder for inhalation．The clinical efficacy, time of symptoms, obvious alleviation and adverse drug reactions were compared between two groups．Result:The total effective rate was 95.0% for the observation group and 80.0% for the controlled group，the clinical efficacy of the observation group was better than that of the controlled group （P＜0.05） and the time of cough alleviation，expectorate alleviation and asthma alleviation in the observation group were obviously shorter than those in the controlled group （P＜0.05）.There was no severe adverse drug reaction side in two groups．Conclusion:Budesonide and formoterol fumarate powder for inhalation were obviously effective for AECOPD with slight adverse drug reaction． |
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