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| 微生态制剂预防老年危重患者抗菌药相关性腹泻疗效观察 |
| Clinical Observation of the Effect of Microecological Agents on the Prevention of Antibiotic Associated Diarrhea in Critically Ill Elder Patients |
| 投稿时间：2011-04-27 修订日期：2011-06-30 |
| DOI： |
| 中文关键词: 老年危重症患者 微生态制剂 抗菌药相关性腹泻 |
| 英文关键词:Critically ill elder patients Microecological modular Antibiotic associated diarrhea |
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| 中文摘要: |
| 摘 要 目的：探讨微生态制剂对于老年危重患者抗菌药相关性腹泻的预防作用。方法：选择2004年12月～2008年12月应用抗菌药治疗的住院老年危重患者218例，根据抗感染治疗同时是否应用微生态制剂（金双歧）随机分为预防组（110例）和对照组（108例），观察两组抗菌药相关性腹泻（AAD）发生情况。结果： 预防组AAD发生13例，发生率11.82%；对照组AAD发生36例，发生率33.33%，预防组AAD发生率明显低于对照组（P<0.01）。预防组AAD发生时间（7.65±2.80）d，病程（3.17±2.85）d，对照组AAD发生时间（5.50±2.47）d，病程（5.86±2.88）d。两组比较差异有统计学意义。结论：微生态制剂（金双歧）有助于防止老年危重患者AAD发生。 |
| 英文摘要: |
| ABSTRACT Objective:To investigate the preventive efficacy of microecological modular on antibiotic associated diarrhea(AAD) in critically ill elder patients. Method:208 critically ill elder patients collected from Dec. 2004 to Dec. 2008 were divided into the prevention group (110) who received their anti-infection treatment, and the controlled group (108) who were given Golden Bifid or not. Their occurrence condition of diarrhea was compared.Result:AAD occurred to 13 of the 110 elder patients in prevention with the incidence of 11.28% while AAD occurred to 36 of the 108 elder patients in the controlled group with the incidence of 33.33%(P<0.01). The mean duration of diarrhea was (7.65±2.80)d for the prevention group and (5.50±2.47)d for the controlled group. The disease courses of the two groups were respectively (3.17±2.85)d and (5.86±2.88)d. There were significant difference between the two groups in both indicators (P<0.01).Conclusion:Microecological modular (Golden Bifid) could be used to prevent AAD in critically ill elder patients effectively. |
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