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| 6种中药注射剂在脑梗死治疗中的不良反应文献分析 |
| Investigation and Analysis of Adverse Drug Reactions of Six Traditional Chinese Medicine Injections |
| 投稿时间：2012-02-03 修订日期：2012-04-28 |
| DOI： |
| 中文关键词: 中药注射剂 药品不良反应 脑梗死 文献调查 合理用药 |
| 英文关键词:Traditional Chinese medicine injection Adverse drug reactions Cerebral infarction Reference investigation Rational drug use |
| 基金项目: |
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| 中文摘要: |
| 摘 要 目的：探讨6种中药注射剂在脑梗死治疗中引起不良反应的特点及发生原因，为临床合理用药提供参考。方法：采用回顾性研究方法，对KNS5.0数据库（中国知网）和万方数据库1994～2011年报道的有关银杏达莫等6种常用中药注射剂在脑梗死治疗中出现的不良反应病例进行统计分析。结果：46岁以上年龄组不良反应构成比较高；多在用药半小时内发生；且不良反应类型以严重的为主，损害类型以全身性损害为主。各种中药注射剂致不良反应在性别、年龄、不良反应发生时间、不良反应类型等有各自的特点。结论：应重视中药注射剂治疗脑梗死所致不良反应，加强监测，促进临床合理用药。 |
| 英文摘要: |
| ABSTRACT Objective:To study the general pattern and characteristics of adverse drug reactions(ADRs) induced by 6 traditional Chinese medicine injections (tcmi) in the cerebral infarction treatment．Methods:A retrospective analysis was conducted on 52 reports of ADR resulting from traditional Chinese medicine injections from 1994 to 2011 retrieved from CHKD and Wanfang database．Results:The adverse reactions induced by 6 tcmi highly occurred to the 46 year-old age group． Most of the ADRs appeared within half an hour after injecting the drug. The main type of ADRs were serious and the damage reactions were systemic damages．All sorts of the adverse reactions induced by tcmi had their respective laws and characteristics．Conclusion:ADRs induced by 6 tcmi in the cerebral infarction treatment should be put an emphasis on by clinical pharmacists and doctors. And the use of tcmi should be under strict minitor to assure the rationd drug use. |
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