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| 615例药品不良反应报告分析 |
| Analysis of 615 ADR Reports |
| 投稿时间：2012-12-19 修订日期：2012-04-23 |
| DOI： |
| 中文关键词: 药品不良反应 监测 合理用药 |
| 英文关键词:Adverse drug reaction Monitoring Rational drug use |
| 基金项目: |
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| 中文摘要: |
| 摘 要 目的：了解某三甲医院药品不良反应（ADR）发生的特点，促进合理用药。方法：对某三甲医院2009 年7月～2011 年6月收集到的615例ADR报告进行回顾性调查。结果：>60岁人群发生ADR的比例最高，有160 例（26.02%）；静脉滴注引起的ADR有516 例（83.90％）；ADR主要累及的器官为皮肤及其附件，有285例（43.91%）；严重ADR 23例，其中以发生过敏性休克为主，有13例；引起ADR的药品有16类171种，抗菌药居首位，有346例（44.88%），抗菌药中以喹诺酮类药物居首位，有81例（23.41%）。结论：加强合理用药教育和对ADR的监测，可减少和避免ADR的发生。 |
| 英文摘要: |
| ABSTRACT Objective: To probe into the characteristics of ADRs in a three A hospital to promote the rational use of drugs. Methods:ADR cases collected from a three A hospital between July 2009 and June 2011 were retrospectively analyzed. Results:The incidence of ADR cases was the highest in patients above 60 years old（n=160,26.02%）. 516 ADR cases were induced by intravenous administration（83.90%）. Main clinical manifestation in 285 cases were lesion of skin and its appendices（43.91%）. The incidence of allergic shock was the highest（n=13）of the 23 severe ADR cases，16 categories（171 kinds）of drugs led to ADRs, in which the incidence of ADRs caused by antibiotic was the highest（n=346,44.88%）；Of the antibiotics the incidence of quinolones was the highest（n=81,23.41%）.Conclusion:Attention should be attached to the education of rational drug use and the ADR monitoring to reduce and avoid the incidence of ADRs. |
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