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| 61例抗糖尿病药物不良反应报告分析 |
| Analysis of 61 Adverse Drug Reaction Reports of Antidiabetics in Diabetes Mellitus |
| 投稿时间：2012-05-16 修订日期：2012-08-02 |
| DOI： |
| 中文关键词: 抗糖尿病药物 药品不良反应 监测 |
| 英文关键词:Antidiabetics Adverse drug reaction Drug monitoring |
| 基金项目:上海医院药学科研基金资助（编号:2010-YY-02-15） |
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| 中文摘要: |
| 摘 要 目的：分析我院抗糖尿病药物不良反应（ADR）发生的特点，为临床合理安全使用该药提供参考。方法：采用回顾性方法，对我院2009年9月～2011年9月临床上报的ADR报告进行统计分析。结果：抗糖尿病药物导致ADR病例61例，其中男30例（49.18%），女31例（50.82%）；涉及药物共6类10种。ADR 临床表现主要为神经系统（35.11%）、消化系统（21.28%）及心血管系统（14.89%）反应。结论：抗糖尿病药物可引发多系统的不良反应，应引起医护人员和患者的关注，注意监测。 |
| 英文摘要: |
| ABSTRACT Objective:To analyze the features of adverse drug reaction(ADR) induced by antidiabetics in diabetes mellitus for reference of rational drug use in the clinic.Methods:61 ADR cases were collected from September 2009 to September 2011 and analyzed retrospectively. Results:Among 61 cases, there were 30 male cases(49.18%) and 31 female cases(50.82%), the male and female ratio being 0.97∶1. The ADR reports were involved in 10 kinds of antidiabetic drugs. The clinical manifestations of ADR included the nervous system (35.11%), digestive system (21.28%) and cardiovascular system (14.89%). Conclusion:The antidiabetics often caused multisystemic ADRs, so more attention should be paid to avoiding the occurrence of ADR by medical staff and patients. |
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