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| 稳定性心绞痛患者PCI围手术期血浆超敏C反应蛋白与血管再狭窄 |
| The Relationship Between hs-CRP and Restenosis in Stable Angina Patients During PCI |
| 投稿时间：2011-09-25 修订日期：2011-11-30 |
| DOI： |
| 中文关键词: 稳定性心绞痛 PCI术 C反应蛋白 支架内再狭窄 |
| 英文关键词:Stable angina Coronary stenting CRP Restenosis |
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| 中文摘要: |
| 摘 要 目的：探讨超敏C反应蛋白（hs-CRP）在稳定性心绞痛患者PCI围手术期中的变化与术后再狭窄的关系。方法：分析78例稳定性心绞痛患者临床资料，分析其在PCI术前、术后即刻、术后24 h、术后72 h及复查冠脉造影前的超敏hs-CRP水平；术后6个月行冠脉造影复查后分为再狭窄组（10例）及无再狭窄组（68例）；比较两组hs-CRP水平。结果：再狭窄组与无再狭窄组比较，两组各项临床特征差异无统计学意义；PCI术后所有患者的hs-CRP水平与术前相比均有明显升高，而且再狭窄组患者术后72 h hs CRP水平高于无再狭窄组（9.81±4.76 vs6.64±2.89，P＜0.01），术后24 h时再狭窄组hs CRP水平高于无再狭窄组（3.77±1.52 vs2.43±1.05，P＜0.05）。结论：稳定性心绞痛患者PCI术后24 h、72 h时hs-CRP明显增高时，提示患者可能出现支架内再狭窄。 |
| 英文摘要: |
| ABSTRACT Objective: To evaluate the relationgship between hs-CRP and restenosis in stable coronary artery disease patients during PCI. Method:clinical data of 78 stable angina patients were retrospectively analyzed. The levels of hs-CRP pre-PCI, pos-PCI, 24-hours-after PCI (24h-PCI) and 72-hours-after PCI (72h-PCI) were respectively measured. Their coronary angiographies were executed again 6-months after PCI. According to the results, those patients were divided into restenosis group (10 cases) and controlled group (68 cases).Result:There was no significant difference in the clinical features between the two groups; In all the patients after PCI, the level of hs-CRP was significantly higher than that before PCI. In the restenosis group, the level of hs CRP 72h -PCI was higher than that in the controlled group （9.81±4.76 vs 6.64±2.89，P＜0.01） and the level of hs-CRP 24h PCI was higher in the restenosis group than that in the controlled group(3.77±1.52 vs2.43±1.05，P＜0.05).Conclusion:In the patients with stable angina, the increasing level of hs-CRP after PCI indicated the possible appearance of restenosis after PCI. |
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