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| 依巴斯汀片治疗急性荨麻疹的疗效观察 |
| Observation of Clinical Efficacy of Ebastine on Acute Urticaria |
| 投稿时间：2011-10-24 修订日期：2011-12-29 |
| DOI： |
| 中文关键词: 依巴斯汀 荨麻疹 急性 疗效 药品不良反应 |
| 英文关键词:Ebastine Acute urticaria Clinical efficacy Adverse drug reaction |
| 基金项目: |
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| 中文摘要: |
| 摘 要 目的：观察依巴斯汀治疗急性荨麻疹的疗效及安全性。方法：80例患者随机分为2组各40例，观察组予依巴斯汀片10 mg,po qd，对照组予酮替芬片1 mg,po bid。观察2组疗效及不良反应。结果：两组患者服药1 h症状积分比较，差异有统计学意义（P＜0.05），服药1 h 、3 h、24 h疗效比较，差异无统计学意义（P＞0.05）；2组不良反应发生率分别为7.5%和47.5%。结论：依巴斯汀治疗急性荨麻疹有效、安全，值得临床应用。 |
| 英文摘要: |
| ABSTRACT Objective: To observe the efficacy and safety of Ebastine against acute urticaria.Method:80 patients with acute urticaria were randomly divided into two groups. The observation group was treated with 10mg of Ebastine daily and the controlled group, treated with 1mg of Ketotifen daily. Their therapeutic effect and adverse drug reaction (ADR) were recorded.Result:There was statistically significant difference between the two groups in one hour in symptom scores, but no statistically significant difference between the two groups in1 hour, 3 hours and 24 hours in clinical efficacy. The incidence rate of ADR in the two groups was 7.5% and 47.5%. Conclusion:Ebastine was effectve and safe for acute urticaria and could be used in clinics. |
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