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| 莫西沙星不良反应文献分析 |
| Literature Analysis of Moxifloxacin induced Adverse Drug Reactions |
| 投稿时间：2012-02-20 修订日期：2012-05-10 |
| DOI： |
| 中文关键词: 莫西沙星 药品不良反应 文献分析 |
| 英文关键词:Moxifloxacin Adverse drug reactions Literature analysis |
| 基金项目: |
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| 中文摘要: |
| 摘 要 目的：探讨莫西沙星所致不良反应的类型及其特点，为临床安全用药提供参考。方法：在中国科技期刊数据库（维普资讯）和中国期刊全文数据库（中国知网）中，以“莫西沙星”和“不良反应”为关键词，搜索2005年～2011年11月莫西沙星所致不良反应文献，并进行统计分析。结果：收集到62例莫西沙星导致的不良反应，主要类型有神经系统反应（28.4%）、过敏反应（21.6%）、心血管系统反应（14.9%）、消化系统反应（10.8%）、呼吸系统反应（6.8%）等。70岁以上的患者占46.8%（29/62），高于其他年龄段。静脉滴注给药者占59.7%（37/62）。结论：临床应高度重视莫西沙星的不良反应，加强用药监护。 |
| 英文摘要: |
| ABSTRACT Objective:To explore the type and characteristics of adverse drug reactions (ADRs) induced by moxifloxacin to provide reference for the clinical rational use of drugs. Methods:Based on the VIP and CNKI database，literatures about moxifloxacin-induced ADRs from 2005 to 2011 were collected and statistically analyzed. Results:In 62 case of patients，main clinical manifestations of moxifloxacin-induced ADRs were nervous system reactions(28.4%)，allergic reactions(21.6%)，cardiovascular system reactions(14.9%)，digestive system reactions(10.8%)，respiratory system reactions (6.8%)，etc. The patients aged more than 70 were 29 cases, accounting for 46.8%. Intravenous drips were 37 cases, accounting for 59.7%. Conclusion:In clinical application，more attention should be paid to the moxifloxacin induced ADRs，and the strict monitor of the drug use should be strenghtened. |
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