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| 2006～2011年我院铜绿假单胞菌检出分布与药敏变迁 |
| Analysis of Pseudomonas Aeruginosa Distribution and Drugs’ Sensitivity in our Hospital During the Period of 2006-2011 |
| 投稿时间：2012-04-11 修订日期：2012-05-30 |
| DOI： |
| 中文关键词: 关键词 抗菌药 铜绿假单胞菌 耐药 |
| 英文关键词:Antibacterials Pseudomonas aeruginos Antimicrobial resistance |
| 基金项目: |
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| 中文摘要: |
| 摘 要 目的：了解我院临床分离铜绿假单胞菌（PA）分布及药敏变迁，为临床合理使用抗菌药提供依据。方法：回顾性分析2006～2011年医院临床分离754株PA的临床分布及药敏结果。结果：754株PA主要分离自痰液、分泌物、尿液；主要分布在ICU、神经外科及呼吸内科；PA对阿米卡星、头孢吡肟、左氧氟沙星、哌拉西林/他唑巴坦、头孢哌酮/舒巴坦耐药率较低为0～11.5%，其次为头孢哌酮、头孢他啶，为7.8%～29.0%；头孢曲松最高为50.0%～63.6%。结论：本院PA耐药性控制较好，但有上升趋势；应继续加强抗菌药应用管理，降低病原菌耐药性。 |
| 英文摘要: |
| ABSTRACT Objective:To study the clinical distribution，epidemic trend and transition of drugs’ sensitivity of Pseudomonas aeruginosa(PA) isolated in recent 6 years to provide reference for the clinical use of antibiotics．Methods:The distribution and resistance of 754 strains of PA isolated from 2006 to 2011were analyzed．Results:A total of 754 strains of PA were mostly isolated from phlegm，secretion and urine. PA was mostly sent from the ICU and departments of neurosurgery and respiratory medicine. The resistant rate of PA to amikacin，cefepime，levofloxacin，piperacillin/tazobactam and cefoperazone/sulbactam was the lowest (0.0%-11.5%)，and the next was cefoperazone and ceftazidime(7.8%-29.0%). The resistant rate of ceftriaxone was the highest(50.0%-63.6%).Conclusion:The drug resistance status of PA was well controlled in our hospital，but still showed its rise． The hospital should continue to strengthen the application of antimicrobial agent management to reduce the pathogen resistance. |
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