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| 2011年杭州地区12家医院质子泵抑制药用药合理性分析 |
| Analysis of Rationality of the Use of Proton Pump Inhibitors in 12 Hospitals in Hangzhou Area in 2011 |
| 投稿时间：2012-05-04 修订日期：2012-07-12 |
| DOI： |
| 中文关键词: 质子泵抑制药 药物利用 合理用药 |
| 英文关键词:Proton pump inhibitors Drug utilization Rational drug use |
| 基金项目: |
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| 中文摘要: |
| 摘 要 目的：了解杭州地区12家医院2011年质子泵抑制药（PPIs）用药的现状及合理性。方法：采用金额排序、用药频度（DDDs）排序，了解该地区12家医院PPIs使用情况；制定PPIs合理用药评价标准，评价PPIs用药合理性。结果：该地区12家医院PPIs使用量泮托拉唑>奥美拉唑>埃索美拉唑镁>雷贝拉唑>兰索拉唑；PPIs处方数31 929张，不合理处方13 535张。不合理使用主要表现为用药指征不合理（60.53%）、用法不合理（17.63%）、用量不合理（9.46%）。结论：该地区PPIs使用存在较多不合理之处，建议颁布PPIs使用规范，同时加强监督管理，确保临床合理用药。 |
| 英文摘要: |
| ABSTRACT Objective:To understand the present status of the use of proton pump inhibitors (PPIs) in 12 hospitals in the Hangzhou area in 2011. Methods:Sorting the amount of cost and frequency of drug use (DDDs) was adopted to understand PPIs use in the 12 hospitals, formulate the rational use of drugs and evaluate the rationality of PPIs. Results:The PPIs usage was ranked as follows: Pantoprazole> Omeprazole> Esomeprazole magnesium> Rabeprazole> Lansoprazole in the 12 hospitals. Unreasonable prescriptions had 13 535 of the 31 929 PPIs prescriptions. The irrational uses were mainly unreasonable use indications(60.53%), unreasonable usage(17.63%), and unreasonable dosage(9.46%). Conclusion:There were many unreasonable PPIs uses in the region. It is suggested that some guidelines should work out to regulate the use of PPIs. Meanwhile，administration supervision and management should be strengthened to ensure rational drug use. |
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