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| 综合指标法评价我院围手术期预防用抗菌药干预措施 |
| Evaluation of Effect of Intervention Measures for Perioperative Prophylactic Antibacterial Drug Use in a Hospital by Comprehensive Index Method |
| 投稿时间：2012-07-17 修订日期：2012-08-14 |
| DOI： |
| 中文关键词: 综合指标法 抗菌药专项整治 干预措施 预防用药 合理用药 |
| 英文关键词:Comprehensive index method Antibacterial drug special rectification Double intervention measures Prophylactic Rational drug use |
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| 中文摘要: |
| 摘 要 目的：评价我院抗菌药专项整治实施双重干预措施（技术干预和行政干预）对围手术期抗菌药不合理应用的效果。方法：将我院专项整治前2011年1～3月120份出院患者病历设为非干预组，专项整治干预后2012年1~3月120份出院患者病历设为干预组，采用综合指标法对2组患者抗菌药应用情况进行对比分析。结果：与非干预组相比，干预组平均药品费用、平均抗菌药费用均明显降低（P<0.01），平均抗菌药费用由 （1 706.92±1 228.32）元降低至（257.17±65.61）元；干预后，Ⅰ、Ⅱ类切口手术术前0.5～2 h内给药比例从6.67%上升至33.33%；合理用药比例从1.67%上升至81.67%，预防用药合理性比例2组差异有统计学意义（P<0.01）。结论：通过抗菌药专项整治实施双重干预措施，可提高抗菌药临床应用的合理性，为医院规范抗菌药应用、降低单病种费用提供了一种有效可行的模式。 |
| 英文摘要: |
| ABSTRACT Objective:To evaluate the effect of special rectification dual intervention (technical intervention and administrative intervention ) of antibacterial drugs on irrational use of antimicrobial agents in the perioperative period in a hospital. Methods:120 medical records of discharged patients in the hospital from Jan. to Mar. 2011 before antibacterial drug special rectification were the non intervention group, and the other 120 were the intervention group. The application of antimicrobial agents of the two groups was comparatively analyzed with the comprehensive index method.Methods:Compared with the non intervention group, the average drug cost and average antimicrobial agents cost of the intervention group decreased obviously to some extent(P<0.01, and especially, the average antimicrobial agents cost decreased from1 706.92±1 228.32 yuan to 257.17±65.61 yuan. The proportion of the drug use before operation 0.52h ofⅠand Ⅱincision operation increased from 6.67%to 33.33%. The proportion of reasonable drug use increased from 1.67%to81.67%. The proportion of reasonable prophylactic drug use had a very significant difference between the two groups（P<0.01）. Conclusion:The double intervention measure through the special rectification of antibacterial drugs were significantly effective and feasible for improving the rationality of clinical application of antimicrobial agents and further standardizing application of antimicrobial agents reduced the cost of single diseases. |
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