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| 普拉克索治疗原发性不宁腿综合征临床观察 |
| Clinical Observation of the Treatment of Primary Restless Legs Syndrome with Pramipexole |
| 投稿时间：2012-08-01 修订日期：2012-10-15 |
| DOI： |
| 中文关键词: 普拉克索 原发性不宁腿综合征 疗效 |
| 英文关键词:Pramipexole Primary restless legs syndrome Treatment effect |
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| 中文摘要: |
| 摘 要 目的：观察普拉克索治疗原发性不宁腿综合征的疗效及安全性。方法：21例原发性不宁腿综合征患者应用普拉克索逐步加量治疗的方法，采用自身前后对照，以不宁腿严重程度量表（IRLS）、匹兹堡睡眠质量指数( PSQI)、汉密尔顿焦虑量表（HAMA）评估疗效。 结果：治疗后21例患者的IRLS、PSQI、HAMA分值较治疗前均有不同程度的下降，差异有统计学意义（P<0.05）。结论：普拉克索治疗原发性不宁腿综合征疗效较好，不良反应相对轻微，对老年不宁腿综合征患者较适合。 |
| 英文摘要: |
| ABSTRACT Objective:To observe the effect and safety of pramipexole on the treatment of primary restless legs syndrome. Methods:21 cases of primary restless legs syndrome were retrospectively analyzed. Pramipexole was dosed up with the treatment, and the international RLS study group rating scale (IRLS), Pittsburgh Sleep Quality Index (PSQI) and Hamilton Anxiety Scale (HAMD) were used to evaluate the effect.Methods:The scores of IRLS, PSQI, and HAMA for 21 patients declined in various degrees, and the differences were significant(P<0.05) .Conclusion:Pramipexole had a positive effect on the treatment of primary restless legs syndrome and low adverse reaction, which is suitable for the senile patients of restless legs syndrome. |
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