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| 药学干预前后我院Ⅰ类切口手术预防用抗菌药比较 |
| Comparison of the Application of Preventive Antibiotics for Type Ⅰ Incision Operation before and after Pharmaceutical Interference |
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| DOI： |
| 中文关键词: 抗菌药 干预 Ⅰ类切口手术 围手术期 合理用药 |
| 英文关键词:Type Ⅰ incision operation Antibiotics Interference Rational drug use |
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| 中文摘要: |
| 摘 要 目的：评价我院临床药师干预前、后Ⅰ类切口手术围术期抗菌药的应用情况与效果比较。方法：对我院2010年7～12月和2011年7～12月Ⅰ类切口手术预防用抗菌药的使用率、应用种类与频次、给药时机、用药时限、费用等进行统计分析。结果：实施药学干预后，我院Ⅰ类切口手术预防用抗菌药使用率由100%降至48.33%，第1代头孢菌素应用率由0升至63.79％；术前0.5～2 h预防用抗菌药比例由17.92％提高至95.59％；术后用抗菌药时间≤24 h的比例由23.33％提高至81.03％；平均用药时间由4.5 d缩短至1.9 d；平均抗菌药费用由635.69元降至256.57元。结论：实施药学干预可显著提高围术期抗菌药合理应用，对合理使用抗菌药有积极促进作用。 |
| 英文摘要: |
| ABSTRACT Objective:To evaluate the application and effects of antibiotics used before and after pharmaceutical interference by clinical pharmacists during the preoperative period of type Ⅰ incision operation. Methods:The patients’ statistics, varieties, frequency, time of drug delivery, administration duration and antibiotics expenses were gathered and analyzed for their type Ⅰ incision operations from July to December of 2010 and from July to December of 2011. Results:After the pharmaceutical interference, the cephalosporin (first generation) used in our hospital was increased from 0 to 63.79%. The ratio covered by the preventive antibiotics that were used 0.5 to 2 hours before the operation was increased from 17.92% to 95.59%. The ratio for the duration not more than 24 hours of antibiotics administration was increased from 23.33% to 81.03%. The average drug administration time was shortened from 4.5 days to 1.9 days. The average expense for antibiotics was decreased from 635.69 yuan to 256.57 yuan. Conclusion:The implementation of pharmaceutical interference could significantly facilitate the reasonable application of antibiotics during the preoperative period, thus boosting the safe, effective, reasonable and economic administration of drug for patients. |
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