|
| 雷贝拉唑联合莫沙必利治疗功能性消化不良41例 |
| Curative Effect of Rabeprazole Combined with Mosapride on 41 Patients with Functional Dyspepsia |
| |
| DOI： |
| 中文关键词: 功能性消化不良 雷贝拉唑 莫沙必利 |
| 英文关键词:Functional dyspepsia Rabeprazole Mosapride |
| 基金项目: |
|
| 摘要点击次数: 994 |
| 全文下载次数: 1224 |
| 中文摘要: |
| 摘 要 目的：观察雷贝拉唑联合莫沙必利治疗功能性消化不良(FD)的疗效。方法：80例FD患者随机分为观察组41例和对照组39例。两组患者均予莫沙必利胶囊5 mg，po tid（餐前30 min服用），连续服用8周。观察组在此础上加用雷贝拉唑钠肠溶胶囊10 mg，po qd，连续服用8周。随访观察6个月，比较两组临床疗效和不良反应。结果：治疗8周后，观察组疗效显著高于对照组(P<0.05)。观察组出现不良反应2例，对照组出现不良反应4例，症状均较轻，不影响治疗。随访观察6个月，观察组复发率明显低于对照组(P<0.05)。结论： 雷贝拉唑联合莫沙必利治疗FD，能持续缓解患者的临床症状，安全性好，复发率低。 |
| 英文摘要: |
| ABSTRACT Objective:To observe the curative effect of rabeprazole combined with mosapride on 40 patients with functional dyspepsia(FD). Methods: 80 patients with FD were randomly divided into the observation group and controlled group. All the patients took mosapride capsule 5mg orally, 3 times a day, half an hour before meal for 8 weeks. The patients of the observation group got extra treatment by taking rabeprazole sodium enteric coated capsules 10mg orally once a day for 8 weeks. The clinic curative effect and adverse reaction were observed for 6 month. Results: 8 weeks after treatment, the curative effect of the observation group was better than that of the controlled group(P<0.05). 2 cases of adverse reaction were found in the controlled group, 1 was bellyache and the other was diarrhea; 4 cases were found in the observation group, 1 was rash and the other 3 were diarrhea. All of these symptoms were mild and did not influence treatment. The responders of the two groups were followed for 6 months. The recurrence rate of the observation group was significantly lower than that of the controlled group(P<0.05). Conclusion: Treating FD with rabeprazole combined with mosapride was safe and could relieve the symptom of the patient and reduce the recurrence rate. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
