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奥卡西平治疗原发性舌咽神经痛的疗效观察
Clinical Analysis of the Effect of Oxcarbazepine in Treating Primary Glossopharyngeal Neuralgia
  
DOI:
中文关键词:  奥卡西平  舌咽神经痛  疗效
英文关键词:Oxcarbazepine  Primary glossopharyngeal neuralgia  Clinical Effect
基金项目:
作者单位
陈剑波 温州医学院附属第六医院耳鼻咽喉头颈外科(浙江丽水323000) 
卢晔芬 温州医学院附属第五医院神经内科。 
黄庆琳 温州医学院附属第六医院耳鼻咽喉头颈外科(浙江丽水323000) 
王小飞 温州医学院附属第六医院耳鼻咽喉头颈外科(浙江丽水323000) 
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中文摘要:
      摘 要 目的:观察奥卡西平治疗舌咽神经痛的临床疗效和安全性。方法:72例患者随机分为观察组和对照组各36例,观察组用奥卡西平治疗,对照组用卡马西平治疗。4周后比较两组疗效和不良反应发生情况。结果:观察组总有效率为75.0%,对照组治疗总有效率为61.1%。两组疗效比较,差异有统计学意义(P<0.05)。观察组疼痛缓解(VAS评分降低)优于对照组,两组比较差异有统计学意义(P<0.05)。观察组不良反应发生率低于对照组(P<0.05)。结论:奥卡西平治疗舌咽神经痛疗效确切,安全可靠,值得临床推广应用。
英文摘要:
      ABSTRACT Objective:To observe the effects and side effects of oxcarbazepine in treating primary glossopharyngeal neuralgia.Methods:72 patients with plimary glossopharyngeal were randomly divided into two groups: observation group and control group. The effects and side effects were compared between the two groups after four weeks.Results:The total effective rate of the observation group was 75.0% and that of the control group was 61.1%. There was significant difference in the total effective rate(P<0.05) and the incidence of side effects (P<0.05)between the two groups. Conclusion:Oxcarbazepine treating primary glossopharyngeal neuralgia had its satisfactory effect and fewer side effects. It is worthy of application in clinic.
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