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某院儿科住院患者药品不良反应调查分析
Analysis of 130 ADR Reports in Children in a Hospital
  
DOI:
中文关键词:  儿童  药品不良反应  监测  报告
英文关键词:Children  Adverse drug reaction  ADR mornitoring  Reports
基金项目:
作者单位
曾晓芳 福建医科大学附属协和医院药学部(福州 350001)。 
刘茂柏 福建医科大学附属协和医院药学部(福州 350001)。 
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中文摘要:
      摘 要 目的:了解某医院儿童药品不良反应(ADR)的发生和分布情况,为临床合理用药提供参考。方法:对某院2010年1~6月收集到的小儿ADR 130例,从性别、年龄、引发ADR的药品种类、给药途径、ADR累及器官或系统及临床表现等方面进行统计分析。结果:年龄<3岁患儿发生ADR的比例最高(82例,63.08%);静脉滴注给药引发ADR的比例最高(97例,74.62%);引起ADR的药品有5类31种,其中抗肿瘤药引起的ADR最多(66例,46.81%)。结论:必须重视小儿ADR的监测和报告,尽量减少或避免ADR发生。
英文摘要:
      ABSTRACT Objective:To investigate the occurrence and distribution of adverse drug reactions (ADR) in pediatrics in a hospital to promote the rational clinical use of drugs.Methods:130 pediatric ADR cases collected from January to June 2010 were analyzed in respect of patients’age, sex, variety of drug, routes of administration,organs or systems involved and clinical manifestations, etc. Results:The incidence of ADR cases was the hightest in the patients under 3 years old (n=82,63.08%),97 cases were induced by intravenous administration (74.62%), 5 categories (31 kinds) of drugs led to ADR, in which the incidence of ADR caused by antineophastic was the highest(n=66,46.81%).Conclusion:Great importance should be attached to the monitor and report of pediatric ADR to reduce or avoid the occurrence of ADR as much as possible.
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