| ABSTRACT Objective: To analyze the clinical characteristics of adverse drug reaction cases caused by insulin to provide reasonable advice for clinical use. Methods:The adverse drug reactions cases caused by insulin were retrieved in the database of Center for ADR Monitoring of Jiangsu to analyze the clinical manifestations, systems involved, types of drugs, etc. Results:143 cases of 289 cases involved were male, and 146 were female. The types of the suspected drugs were mostly regular insulin, ultra short acting insulin and insulin analogue. The systems with adverse drug reactions included the skin and its appendages, metabolism and nutrition disorder and systemic damages. 283 cases were healed or improved after therapy, 2 cases had sequela of partial lipodystrophy, and 4 cases were not healed. Conclusion: Adverse drug reactions caused by insulin occurred in more than one system at the same time; and therefore, clinical medicine use should be closely monitored, and attention should be paid to some rare adverse drug reactions to ensure the safe drug use. |
