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158例药品不良反应报告分析
Analysis of 158 Cases of Adverse Drug Reactions
  
DOI:
中文关键词:  药品不良反应  报告  药物警戒
英文关键词:Adverse drug reaction  Report  Phamacovigilance
基金项目:
作者单位
段雪云 湖北省中医院药事部(武汉 430061)。 
黄正德 湖北省中医院药事部(武汉 430061)。 
陈树和 湖北省中医院药事部(武汉 430061)。 
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中文摘要:
      摘 要 目的:分析我院不良反应发生的特点,为临床合理用药提供参考。方法:收集我院2010~2011年上报的158例不良反应报告,对ADR病例中患者年龄、性别,涉及药品种类、临床表现及累及器官,以及ADR转归、预后等信息进行统计分析。结果:158例ADR报告中以女性及老年患者居多,给药途径以静脉滴注较多,所涉及药品以抗感染药和中成药发生例次较高,临床表现以皮肤过敏及附件损害为主,严重病例10例,无死亡病例。结论:应重视分析ADR报告资料,特别是抗感染药及中药注射剂的临床合理应用,及时将信息反馈给临床,以促进临床合理用药。
英文摘要:
      ABSTRACT Objective:To analyze the characteristics and of adverse drug reaction(ADR) in our hospital and provide references for rational drug use in clinic.Methods:158 ADR cases collected in our hospital from 2010 to 2011 were statistically analyzed in respect of patients’ age and gender, categories of ADR inducing drugs, organs or systems involved in ADR, consequence and prognosis,etc.Results:Among the 158 ADR cases, female and the eldest was the most. The occurrence of ADRs caused by intravenous administration were the highest, and most ADRs were caused by anti infectives and then by traditional Chinese medicine injections. Skin and its appendants damages were the most common clinical manifestations of ADR. There were 10 serious ADRs but nobody died. Conclusion:It is important to analyze the ADR reports and feedback the related information to clinic and more attention should be paid to the standard medication of anti infectives and traditional Chinese medicine injection in order to promote the rational drug use.
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