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| 534例抗菌药不良反应分析 |
| Analysis of Antibiotics Adverse Drug Reaction of 534 cases |
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| DOI： |
| 中文关键词: 抗菌药 药品不良反应 安全用药 |
| 英文关键词:Antibiotics Adverse drug reaction(ADR) Safe medication |
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| 中文摘要: |
| 摘 要 目的：分析抗菌药不良反应（ADR）发生特点，为临床安全用药提供参考。方法：采用回顾性研究方法，统计分析2012年嘉兴市部分医院上报的534例抗菌药ADR病例报告。结果：534例报告共涉及抗菌药12大类51个品种；病例中幼儿的所占比例最大（26.97%）；涉及药品以头孢菌素类所占比例最高（48.31%）；ADR累及系统（器官）以皮肤及其附件受损（63.42%）为主；β-内酰胺类是引起严重ADR的主要抗菌药。结论：应重视抗菌药合理使用，减少和避免ADR的发生，确保临床用药安全。 |
| 英文摘要: |
| ABSTRACT Objective:To analyze the characteristics of antibiotics adverse drug reaction(ADR)，in order to provide reference for security use of drugs．Methods:534 cases of antibiotics induced ADR reports reported to Jiaxing ADR monitoring center in 2012 were analyzed retrospectively．Results:12 categories 51 kinds of antibiotics were involved in the total 534 cases of ADRs．The constituent rate was highest in 0-10 year old patients(26.97％)．Among different kinds of antibiotics，the greatest number of ADR were caused by Cephalosporins (48.31％), The main organs damaged by ADR were skin and its attachments(63.42％). Among different kinds of antibiotics，most of the serious ADR reports were caused by β lactams. Conclusion:ADR monitoring should be strengthened especially for antibiotics to enhance clinical safe drug use consciousness for the security of patients with drugs． |
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