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2010~2012年我院抗菌药使用强度调查
Survey of Antibacterial Use Density in our Hospital during 2010-2012
  
DOI:
中文关键词:  抗菌药  限定日剂量  使用强度  药物利用
英文关键词:Antibacterials  Defined daily dose  Antibiotics use density  Drug utilization
基金项目:
作者单位
程军 安徽蚌埠市第三人民医院药学部(安徽蚌埠 233000) 
张士勇 安徽蚌埠市第三人民医院药学部(安徽蚌埠 233000) 
叶云 安徽蚌埠市第三人民医院药学部(安徽蚌埠 233000) 
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中文摘要:
      摘 要 目的:分析我院住院患者抗菌药的应用情况及趋势,为合理使用抗菌药提供依据。方法:回顾性收集我院2010~2012年出院患者抗菌药的使用记录,以限定日剂量(DDD)为单位,计算抗菌药使用强度(AUD)并进行分析。结果:我院抗菌药使用强度3年来呈下降趋势,由2010年的68.63DDD/100人天下降到2012年的42.61DDD/100人天,尤以手术科室下降明显。头孢菌素类复方制剂、第三代头孢菌素始终位居前3位,喹诺酮类抗菌药使用强度下降明显。结论:我院存在用药过度、用药集中等问题。应严格限制头孢菌素类复方制剂、第三代头孢菌素临床应用,提高合理用药水平。
英文摘要:
      ABSTRACT Objective:To provide an evidence for rational clinical use of antibacterials through analysis of the application and trend of antibacterials in the inpatients of our hospital. Methods: By retrospective study,the data of drug used during 2010 2012 were collected and analyzed. With the defined daily dose(DDD) as the unit,antibacterial use density(AUD)was calculated and its analysis was made .Results:The AUD in our hospital markedly decreased from 68.63DDD /100 persons/d in 2010 to 42.61 DDD/100 persons/d in 2012 in the past 3 year, especially in the surgical departments. Cephalosporins compound preparation and third generation cephalosporins always ranked in the first three places. But quinolones significantly decreased. Conclusion:Antimicrobial drug use in the clinic in our hospital might have such problems as overmedication, dense medication. Cephalosporins compound preparation and third generation cephalosporins should be strictly restricted in clinical application in order to improve the rational use of drugs.
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