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173例中药制剂所致不良反应报告分析
Analysis of 173 Cases of Adverse Reactions in Chinese Patent Medicine
  
DOI:
中文关键词:  中药制剂  药物不良反应  合理用药
英文关键词:Chinese patent medicine  Adverse drug reaction  Rational drug use
基金项目:
作者单位
顾平 遂宁市中心医院药剂科(四川遂宁 629000) 
袁琳 遂宁市中心医院药剂科 
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中文摘要:
      摘 要 目的:分析我院上报的中药制剂相关不良反应,探讨中药制剂不良反应发生特点,为中药制剂临床安全应用提供参考。方法:回顾性调查分析我院2008年7月~2013年6月上报的中药制剂不良反应报告资料。结果:中药制剂不良反应中老年人发生不良反应比例最高(71.68%);活血类中药制剂引起的不良反应例次最多(54.34%);主要临床表现为皮疹、瘙痒;静脉给药(75.14%)是引起不良反应的主要给药途径,其中静脉给药后30 min内是不良反应发生的主要时间段。结论:重视中药制剂相关不良反应,加强监测,以减少中药制剂给患者带来损害。
英文摘要:
      ABSTRACT Objective::To investigate the adverse reaction of Chinese patent medicine and explore the characteristics in the adverse reaction of Chinese patent medicine to provide reference for rational drug utilization.Methods::The total data of adverse reaction of Chinese patent medicine were retrospectively analyzed from July 2008 to June 2013 in our hospital.Results::Incidence of adverse reaction of Chinese patent medicine in old people was the highest (71.68%). Most cases of the adverse reactions (54.34%) were caused by blood circulation of Chinese patent medicine. The most common clinical manifestations were skin rashes and itching.The intravenous administration (75.14%) was the main drug delivery route,especially within the initial 30 min after administrating.Conclusion::More attention should be paid to adverse drug reactions of Chinese patent medicine to strengthen monitoring and reduce the damage to patients.
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