| ABSTRACT Objective:To analyze the distribution and drug resistance of enterococcus in various infection samples to provide references for the clinical treatment. Methods: 729 strains of clinically isolated enterococcus genus were collected from Tongji Hospital in Hubei Province from January 2012 to December 2012. An antimicrobial susceptibility test was performed with Kirby Bauer disc diffusion method and their results were analyzed according to CLSI 2011guideline Results:729 strains of enterococcus were isolated. 219 of them(30.2%) were enterococcus faecalis, 257(35.3%) were enterococcus faecium, 220(30%) were enterococcus sp, and the other enterococcus accounted for 33(5%). These strains mainly coming from urine, drainage and secretion were as follows: 278 strains (38.1%) from urine, 94 strains (12.9%) from drainage, and 75 strains (10.3) from secretion. Enterococcus faecium had a higher resistance rate than enterococcus faecalis to penicillin, ampicillin, high concentration of gentamycin, ciprofloxacin, levofloxacin, erythromycin and furadantin. No linezolid resistant enterococcus faecium was found. Vancomycin, teicoplanin and linezolid had their higher sensitivity to enterococcus, which accounted for 96.4%, 97.9% and 99.9%, respectively.Conclusion:The enterococcus faecalis and enterococcus faecium were the most common cause of nosocomial infection pathogen. The enterococcus was mostly found in the urinary tract infection. The antimicrobial resistance of enterococcus varied greatly according to different types, and most of them were multidrug resistance. Enterococcus isolated from clinical samples should be identified to species as far as possible, so the treatment of enterococcus bacteria’s infection could be based on the drug susceptibility test results and the antibiotics could be more reasonably used. |
