ABSTRACT Objective::To analyze the characteristics of adverse drug reaction (ADR) in Jingmen area of Hubei province and promote clinical rational drug use. Methods:The report units, sex of the patients, types of ADR, drug varieties and result evaluation were analyzed from 1 814 ADR reports in Jingmen area. Results:99.78% of the cases came from the medical institutions, the ratio of male to female was almost equal,ADRs were mainly caused by antibiotics(59.59%), and among the antibiotics the percent of 52.98 cases were caused by β-lactum. The main route of administration was caused by intravenous drip(78.78%), main clinical manifestations of ADRs were lesion of skin and its appendants, and digestive system accounting for 34.43% and 32.12%, respectively. Conclusion:Reporting institutions should pay attention to the monitoring of ADR, improve their monitoring level and reduce the risks of ADR occurrence. |