| ABSTRACT Objective::To analyze the characteristics and rules of fluoroquinolone antibacterial drug adverse reactions to provide reference for clinical rational drug use.Methods::In the retrospective review, a retrospective analysis of 156 cases of fluoroquinolones adverse drug reactions was made from 2008 to 2012. The Excel form including the general condition of patients was established to analyze their medication, adverse reactions, clinical manifestation, treatment of adverse reaction and so on. Results:: The adverse reactions occurred in 89 women and 67 men with an average age of 56.7 years. Adverse reactions were involved in a total of 3 drugs: levofloxacin with 88 cases (56.4%), including 12 cases of serious adverse reactions; moxifloxacin with 58 cases (37.2%), including 12 cases of serious adverse reactions, and ciprofloxacin with 10 cases (6.4%) without serious adverse reactions. Clinical adverse reactions were mainly involved in the digestive system, immune system, nervous system, etc. Adverse reaction routes of administration were intravenous drip. Conclusion:: The clinical application of fluoroquinolone antibacterial drugs were unreasonable, and the monitoring of adverse reactions to antibiotics should be strengthened to ensure the safety of clinical use. |
