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2010~2012年南京地区34家医院抗抑郁药利用情况调查
Analysis of the Use of Antidepressant Drugs in 34 Hospitals of Nanjing During 2010-2012
  
DOI:
中文关键词:  抗抑郁药  销售金额  用药频度  药物利用
英文关键词:Antidepressant drugs  Consumption sum  DDDs  Drug utilization
基金项目:
作者单位
花蓉 南京大学医学院附属鼓楼医院药剂科(南京 210008) 
刘慧 南京大学医学院附属鼓楼医院药剂科(南京 210008) 
刁雨辉 南京大学医学院附属鼓楼医院药剂科(南京 210008) 
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中文摘要:
      摘 要 目的:了解南京地区抗抑郁药应用的情况及趋势。方法: 采用回顾性调查方法,对南京地区34家医院2010~2012年抗抑郁药的主要品种、销售金额、用量和生产厂家等情况进行统计分析。结果:3年中南京地区抗抑郁药的销售金额逐年上升,选择性5 羟色胺再摄取抑制药占销售金额比重最大,购药金额构成比例为70.62%、68.72%、69.07%。选择性5 羟色胺再摄取抑制药各年的用药频度(DDDs)构成比较高,分别为72.25%,70.74%,71.72%。2012年DDDs居于前3位的分别是帕罗西丁、舍曲林和文拉法辛。结论:抗抑郁药在临床治疗中发挥越来越重要的作用,南京地区使用抗抑郁药的结构和层次相对合理,基本符合我国目前抗抑郁药的发展现状。
英文摘要:
      ABSTRACT Objective::To analyze the application and development trend of antidepressant drugs in Nanjing. Methods:The varieties, manufacturers, sales amount and consumption of antidepressant drugs were retrospectively investigated among 34 hospitals in Nanjing during 2010 2012.Methods:The sale of antidepressant drugs in Nanjing was increased year by year and selective serotonin reuptake inhibitor occupied the highest proportion which accounted for 70.62%,68.72% and 69.07% of the sales amount from 2010 to 2012, respectively. As to DDDs, selective serotonin reuptake inhibitors were antidepressant drugs, accounting for 72.25%, 70.74%, 71.72%. Paroxetine, sertraline and venlafaxine were the most commonly used in 2012. Conclusion:Antidepressant drugs played an increasingly important role in clinical treatment. The composition and classification of antidepressant drugs used in Nanjing was relatively reasonable, which was consistent with the development and present situation of antidepressant drugs in China.
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