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利多卡因致过敏性休克84例中文文献综述
Chinese Literature Analysis of 84 Cases Anaphylactic Shock Induced by Lidocaine Injection
  
DOI:
中文关键词:  利多卡因  过敏性休克  文献综述
英文关键词:Lidocaine  Anaphylactic shock  Literature analysis
基金项目:
作者单位
金永新 甘肃省第二人民医院(兰州 730000) 
张鑫 甘肃省第二人民医院(兰州 730000) 
吴玉琼 甘肃省第二人民医院(兰州 730000) 
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中文摘要:
      摘 要 目的:通过文献分析,探讨利多卡因发生过敏性休克的特点和规律。方法:检索《中国生物医学文献数据库》(1978~2013年7月) 、《中国知网》(1994~2013年7月)和《万方医学网》(1994~2013年7月)有关利多卡因引起过敏性休克的文献资料,针对患者年龄、性别、给药途径、原患疾病、ADR 发生时间、临床表现、处理措施、愈后情况、是否有过敏史等进行统计分析。结果:在既往有药物过敏史者中发生率更高;77.38%的患者在用药后5 min内发生过敏性休克。结论:提示临床医生在用药前应仔细询问患者药物过敏史,用药过程应加强观察,全程监护。
英文摘要:
      ABSTRACT Objective::To investigate the features and regularity of anaphylactic shock induced by Lidocaine injection by Chinese literature ananlysis. Methods: Chinese Biological Medical Disc from 1978 to July 2013, China Knowledge Network and Wanfang data from 1994 to July 2013 were retrieved to collect the case reports of anaphylactic shock induced by lidocaine injection. The age, sex, administration route, original disease, occurrence time and clinical symptoms of ADR, treatment measures, recovery and allergic history were statistically analyzed. Results: A higher incidence occurred to patients with drug allergy record, and most of the anaphylactic shock occurred within 5 minutes (77.38%) after administration. Conclusion:The results suggested that clinical doctors should inquire patient's allergic history in detail before treatment and carry out their careful observation and strong monitoring during medication.
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