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1 200例人血白蛋白临床应用分析
Analysis of the Clinical Application of Human Serum Albumin in 1 200 Cases
  
DOI:
中文关键词:  人血白蛋白;临床应用;药物利用评价  合理用药
英文关键词:Human serum albumin  Clinical application  Drug use evaluation  Rational drug use
基金项目:
作者单位
陈丽 湖南省人民医院临床药学办 
邓楠 湖南省人民医院临床药学办 
韦鸿雁 湖南省人民医院临床药学办 
谭波宇 湖南省人民医院临床药学办 
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中文摘要:
      摘 要 目的:评价我院人血白蛋白(HSA)的临床应用情况,为临床合理应用HSA提供参考。方法:利用医院信息管理系统及电子病历系统,回顾性调查我院 2012年7月~2013年6 月应用HSA的住院患者处方1 200张,对HSA的使用情况进行统计分析。结果:1 200张处方共使用HSA 45 960 g;外科用量大于内科,以肝胆外科应用最多;患者单次用量4~20 g不等。447例患者应用HSA有指征,其中最主要的指征包括严重低蛋白血症(54.14%)、肝硬化腹水(26.40%)和心脏手术(15.88%)。753例患者使用HSA不合理。结论:我院HSA应用广泛,且存在过度应用的现象。建议临床严格掌握HSA用药指征,规范用药行为,促进药物合理应用。
英文摘要:
      ABSTRACT Objective:To evaluate the human serum albumin(HSA) utilization for inpatients in our hospital. Methods:A descriptive and retrospective study that included 1 200 patients receiving HSA in our hospital was performed from July 2012 to June 2013. Results:1 200 patients received a total quantity of 45 960 g of HSA during the study. The surgery patients used more dosages than the internal medical patients did and most dosages were used in the liver and gall surgery. The individual consumption quantity ranged from 4g to 20g. Only 447 patients (37.25%) were utilized appropriately according to the guidelines. Among 477 patients, the most common indications to prescribe HSA were severe hypoalbuminemia (54.14%), ascites (26.40%) and volume expansion after the heart surgery (15.88%). There are 753 cases inappropriate preseription of HSA.Conclusion:HSA was widely used in our hospital. The retrospective study highlighted the overuse of HSA. Some educational and informative measures must be established to restrict HSA use for justified indications.
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