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云南白药气雾剂联合重组人表皮生长因子治疗放射性皮炎
Observation of Curative Effect of Yunnan Baiyao Aerosol Combined with rhEGF on the Treatment of Radioactive Dermatitis
  
DOI:
中文关键词:  云南白药气雾剂  放射性皮炎  重组人表皮生长因子
英文关键词:Yunnan Baiyao aerosol  radioactive dermatitis  rhEGF
基金项目:
作者单位
刘桂萍 荆州市第一人民医院(湖北荆州 434000) 
杨德兰 荆州市第一人民医院 
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中文摘要:
      摘 要 目的:观察云南白药气雾剂联合重组人表皮生长因子(rhEGF)治疗Ⅱ、Ⅲ级放射性皮炎的临床疗效及安全性。方法:80例Ⅱ、Ⅲ级放射性皮炎患者随机分成两组,观察组予云南白药气雾剂联用金因肽喷雾治疗,对照组单用金因肽喷雾治疗,观察两组患者创面愈合、创面渗出、红肿消失时间、疼痛消失时间、瘙痒消失时间,比较两组临床疗效及药品不良反应。结果:观察组显效率72.5%,总有效率97.5%;对照组显效率40%,总有效率92.5%。两组比较差异统计学意义(P<0.05)。两组红肿消失时间﹑疼痛消失时间、瘙痒消失时间等分布比较,差异均有统计学意义(P<0.05)。结论:云南白药气雾剂联合rhEGF治疗Ⅱ﹑Ⅲ级放射性皮炎,能提高疗效,且安全性好。
英文摘要:
      ABSTRACT Objective: To observe the Curative effect and safety of Yunnan Baiyao aerosol combined with rhEGFon the treatment of Type Ⅱ, Ⅲ radioactive dermatitis. Methods:80 cases of Ⅱ, Ⅲ radioactive dermatitis were randomly divided into two groups, the observation group were treated with Yunnan Baiyao aerosol combined with rhEGF spray , the control group were treated with the rhEGF spray.The wound healing、 wound exudation、swelling disappearing time、itching disappearing time and pain disappearing time were observed after the treatment,and the clinical curative effect and adverse drug reactions of patients in the two groups were observed. Results:In the observation group, the marked effective rate was 72.5%, the total effective rate was 97.5%, in the control group, the marked effective rate was 40%, the total effective rate was 92.5%.The difference between the two groups was statistically significant (P<0.05). And there were also statistical differences in the two groups of clinical curative effect,the swelling disappearance time,the pain disappearing time,and the itching disappeared time (P<0.05).Conclusion:Yunnan Baiyao aerosol combined with rhEGFin the treatment of Ⅱ, Ⅲ radioactive dermatitiscould improve the curative effect and the safety.
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