| ABSTRACT Objective::To evaluate the clinical efficacy of amiodarone in the treatment of acute myocardial infarction ventricular arrhythmia. Methods:78 acute myocardial infarction ventricular arrhythmia patients were selected in our hospital from January 2011 to December 2012, and were randomly divided into amiodarone group and lidocaine group with 39 cases in each group. The therapeutic effect was observed according to 24h dynamic electrocardiogram in the two groups after treatment, and 24h chamber arrhythmia time frequency, QRS wave (s), PR interval (s) and the occurrence of adverse reactions, observed after treatment. Results:After the treatment, the total effective rate was significantly higher (94.87%) in amiodarone group, than that (82.05%) in lidocaine group, and the difference was statistically significant (P<0.05); after treatment, the onset times of the two groups and QRS waves of ventricular arrhythmias were significantly improved, and the improving condition of amiodarone group was obviously better than that of lidocaine group, and there was significant difference (P<0.05); the incidence of adverse reaction was significantly lower (17.95%) in amiodarone group than that (33.33%) in lidocaine group, and the difference was statistically significant (P<0.05). Conclusion:Amiodarone in the treatment of acute myocardial infarction ventricular arrhythmia was safe and effective, and could significantly improve the cure rate of the patients, reduce the mortality rate with fewer adverse reactions than lidocaine, and was therefore worth the clinical promotion. |
