| ABSTRACT Objective::To observe the application effect of methotrexate and mifepristone on ectopic pregnancy. Methods:58 cases of ectopic pregnant patients were treated in our hospital from January 2010 to January 2013 according to admission order and divided into study group and control group with 29 cases in either group. The control group was treated with methotrexate intramuscular injection, and based on the treatment of the control group, the study group was treated with mifepristone. At the end of the treatment, the cure rate , secondary compliance rate and adverse reaction rate were compared between the two groups. Results: After the treatment, the cure rate of the study group was 93.1% higher than those of the control group (69%) . The difference was statistically significant (P<0.05). The secondary compliance rate of the study group was only 10.3%, significantly lower than 48.4% of the control group, and the difference was statistically significant (P<0.05). The incidence rate of adverse reaction in the study group was 55.2% and 51.7% in the control group, and there was no significant difference (P>0.05).Conclusion:Methotrexate and mifepristone had their accurate efficacy in the treatment of ectopic pregnancy. They could reduce the secondary compliance rate, and the burden of the patients and their family members. The treament is worthy of clinical use. |
