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| 噻托溴铵联合运动训练对慢性阻塞性肺疾病稳定期患者BODE指数影响 |
| Change of BODE index in the Treatment of Chronic Obstructive Pulmonary Disease in Stable Period by Tiotropium Bromide Combined with Exercise |
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| DOI： |
| 中文关键词: 噻托溴铵 运动训练 慢性阻塞性肺疾病 BODE指数 |
| 英文关键词:Tiotropium bromid Exercise Chronic obstructive pulmonary disease BODE index |
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| 中文摘要: |
| 摘 要 目的:观察噻托溴铵联合运动训练对中重度慢性阻塞性肺疾病(COPD)稳定期患者BODE指数的影响。方法：80例中重度COPD稳定期患者按就诊时间顺序分为观察组及对照组各40例。观察组在常规治疗基础上给予吸入噻托溴铵联合运动训练,对照组仅给予常规治疗，观察期为6个月。比较两组患者BODE指数。结果：6个月后观察组BODE指数分值较对照组明显下降（P<0.05），其中6 min步行距离、肺功能指标等均较对照组有明显改善（P<0.05）；而两组体重指数、呼吸困难量表比较，差异无统计学意义（P>0.05）。结论：噻托溴铵联合运动训练能明显改善中重度COPD稳定期患者BODE指数及预后。 |
| 英文摘要: |
| ABSTRACT Objective::To study the change of BODE index in the treatment of chronic obstructive pulmonary disease by tiotropium bromide combined with exercise. Methods::80 COPD patients in their moderate and severe periods were randomly divided into two group (observation group with 40 cases and control group with 40 cases). The observation group received their inhaled tiotropium bromide combined with exercise and conventional treatment, and the control group received their conventional treatment. BODE indexes of the two groups were compared, and the results obtained were statistically analyzed .Results::6 months after ： (1) BODE index score of the observation group was more significantly decreased than that of the control group , and the difference was statistically significant (P<0.05); (2) BODE index［6MWD (6 minutes walking distance), and lung function (FEV1%)］ were improved more in the observation group after the treatment than those of the control group, and the difference was statistically significant (P<0.05); (3) BODE index BMI (body mass index) and MMRC (dyspnea scale) improved in the two groups but there was no significant difference(P>0.05). Conclusion::Tiotropium bromide combined with exercise could significantly improve the moderate and severe stable COPD BODE index and prognosis. |
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