| ABSTRACT Objective::To observe the thoracotomy clinical efficacy and safety of ambroxol hydrochloride injection on the prevention of traumatic pneumothorax pulmonary complications.Methods:Forty three cases of traumatic hemopneumothorax patients were randomly divided into the observation group with 23 patients and the controlled group with 20 cases. The observation group was given preoperative ambroxol hydrochloride injection 30mg plus 0.9% sodium chloride injection 100ml, ivd, qd, after operation, based on the conventional treatment in the controlled group ambroxol hydrochloride injection 30mg plus 0.9% sodium chboride injection 100ml, ivd tid. The patients in the the controlled group were conventionally treated: keeping the airway open, giving oxygen, hemostatic, analgesic anti infection, prevention of stress response, rehydration and other conventional treatment. The postoperative course was 6d. The oxygenation index, procalcitonin (PCT), pulmonary infection and incidence rate of pulmonary atelectasis were measured on the 7th day in both groups.Methods:The oxygenation index and PCT (>0.5 ng·ml-1) of the observation group improved more than those in the controlled group. The incidence rates of pulmonary atelectasi and pulmonary infection in the observation group were lower than those in the controlled group. There was statistically significant difference（P＜0.05）.Conclusion:Ambroxol hydrochloride injection could reduce the thoracotomy pulmonary complications resulting from traumatic pneumothorax. |
