| ABSTRACT Objective:To investigate the clinical application status of anticoagulants in patients with non valvular atrial fibrillation of our hospital and provide the basis for clinical rational use of anticoagulant drugs.Methods:A total of 149 patients with non valvular atrial fibrillation from January 2013 to December 2013 were collected.To analyze and evaluate the clinical application of anticoagulants based on thrombo embolism risk score,bleeding risk score and time in therapeutic range（TTR）.Results:In 149 patients with non valvular atrial fibrillation,110 patients used warfarin as anticoagulation,24 patients used aspirin as anticoagulation,and 10 patients used dabigatran Etexilate as anticoagulation.After thrombo embolism risk assessment,the patients of high risk,moderate risk and low risk with thrombo embolism was 80,46,23 respectively.There were 2 patients with aspirin occurred stroke, and 8 patients with warfarin occurred non serious hemorrhage events.The factors,including elder,more comorbidities,high risk of thrombo embolism and bleeding, affect the choice of anticoagulants.Conclusion:The clinical application status of anticoagulants in patients with non valvular atrial fibrillation of our hospital is well,and fundamentally accorded with the recommended anticoagulants in foreign guidelines . |
