|
| 窄谱中波紫外线联合复方甘草酸苷治疗湿疹近期疗效观察 |
| Recent Observation on the Combination of NB-UVB and Compound Glycyrrhizin to Treat Eczema |
| |
| DOI： |
| 中文关键词: 窄谱中波紫外线 复方甘草酸苷 湿疹 |
| 英文关键词:NB-UVB Compound Glycyrrhizin Eczema |
| 基金项目: |
|
| 摘要点击次数: 1391 |
| 全文下载次数: 2222 |
| 中文摘要: |
| 摘 要 目的:探讨窄谱中波紫外线（NB-UVB）联合复方甘草酸苷治疗湿疹的临床疗效和安全性。方法：150例泛发性湿疹患者随机分为观察组和对照A组、对照B组等三组各50例,分别采用NB-UVB联合复方甘草酸苷120 mg，ivd qd、单独复方甘草酸苷120 mg，ivd qd以及单用NB-UVB照射治疗。治疗两周后比较三组EASI评分、临床疗效与药品不良反应发生情况。结果：观察组总有效率为90%，明显优于对照A组（70%）和B组（62 %），差异有统计学意义 (P<0.01)。三组患者均未见明显药品不良反应。结论：NB-UVB联合复方甘草酸苷治疗湿疹疗效明显高于单纯复方甘草酸苷治疗，是治疗湿疹的有效方法之一。 |
| 英文摘要: |
| ABSTRACT Objective:To explore the recent effects and safety of combination of narrow band ultraviolet B(NB-UVB) and Compound Glycyrrhizin to treat eczema. Methods:150 patients with eczema were randomly selected into three groups, i.e. therapy group (50 cases), control group A (50 cases) and control group B(50 cases). Patients in therapy group were received Compound Glycyrrhizin 120mg every day for two weeks by intravenous drip, along with NB-UVB treatment. Patients in control group A were only received Compound Glycyrrhizin by the same way used in therapy group. Patients in control group B were treated with NB-UVB only. The assessment of the clinic effects were made two weeks after the beginning of treatment.Results:After treatment, EASI score of the skin lesion area and skin exfoliation in therapy group were remarkably lower than those in control group B(P<0.05). The total effective rates of control group A and control group B were 70% and 62%, whereas that in therapy group was 90% with a significantly difference compared with both control groups (P<0.025 or0.01). During the whole period of treatment, no adverse drug reactions that could terminate the research were observed. Conclusion:Combination of NB-UVB and Compound Glycyrrhizin is better than alone usage of Compound Glycyrrhizin, suggesting an effective method in the treatment of eczema. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
