ABSTRACTThe current widely used prescription and non prescription drugs in many contain acetaminophen, in recent years overdose acetaminophen induced liver toxicity caused by the increasingly attention of the clinician and management. The article through to the hepatotoxicity of acetaminophen related literature is reviewed, summary of pharmacoepidemiology, pathogenesis of acetaminophen induced liver toxicity, the correlation between liver toxicity and drug dose, and the relevant treatment, for the purpose of safe and reasonable to provide clinicians with the drug valuable reference. |