国家科技部中国科技论文统计源期刊   中国科技核心期刊   WHO西太平洋地区医学索引(WPRIM)收录期刊   湖北优秀期刊
《药物流行病学杂志》官方网站与投审稿系统变更通知<点击查看详情>
665株鲍曼复合醋酸钙不动杆菌临床分布及耐药分析
Resistance Tendency Analysis and Clinical Distribution of 665 Acinetobacter Calcoaceticus Acinetobacter Baumannii Composite
  
DOI:
中文关键词:  鲍曼复合醋酸钙不动杆菌  耐药  医院感染
英文关键词:Acinetobacter calcoaceticus-Acinetobacter baumannii composite  Drug resistance  Nosocomial infection
基金项目:
作者单位
王思颖 湘潭市中心医院药物临床试验机构(湖南湘潭 411100) 
摘要点击次数: 861
全文下载次数: 1246
中文摘要:
      摘 要 目的:研究我院临床分离的鲍曼复合醋酸钙不动杆菌的耐药情况及其临床分布,为合理使用抗菌药提供依据。方法:收集2014年1~6月的临床标本, 分离菌株,收集并分离鲍曼复合醋酸钙不动杆菌,采用K B法进行药敏试验。采用WHONET 统计软件对其结果进行分析。结果:我院鲍曼复合醋酸钙不动杆菌感染科室主要集中在呼吸内科、EICU、SICU、神经内科;痰标本中分离最多(84.81%)。鲍曼复合醋酸钙醋酸钙不动杆菌复合体对抗菌药物耐药率高于75%的依次为呋喃妥因(100.0%)、哌拉西林(88.5%)、头孢噻肟(88.5%)、美罗培南(84.6%)、氨曲南(83.0%)、多西环素(82.9%)、环丙沙星(82.8%)、头孢吡肟(82.2%)、阿米卡星(81.3%)、头孢他啶(79.0%)、哌拉西林/他唑巴坦(78.3%)、亚胺培南(77.1%)、氨苄西林/舒巴坦(75.6%)。结论:医院内获得性鲍曼复合醋酸钙不动杆菌对多种抗菌药物耐药,应加强对其耐药性的监测,合理使用抗菌药物。
英文摘要:
      ABSTRACT Objective:To research resistance and distribution characteristic of clinical isolated Acinetobacter calcoaceticus-Acinetobacter baumannii composite(A.calcoaceticus-A.baumannii composite)of Xiangtan central hospital,to provide evidence for rational use of antimicrobial agents. Methods:A.calcoaceticus-A.baumanniicomposite from first isolated clinical submission specimens of January 1, 2014-June 31, 2014 inpatient in Xiangtan central hospital were collected and separated,using VITEK 32 type automatic microbial analyzer. KB method was used to test drug susceptibility. WHONET statistical software was used to analyze its results. Results:The resistant rates of A.calcoaceticus A.baumannii composite for respective antibiotics were: nitrofurantoin 100%, piperacillin 88.5%, cefotaxime 88.5%, meropenem 84.6%, aztreonam 83.0%, deoxytetracycline 82.9%, ciprofloxacin 82.8%, cefepime 82.2%, amikacin 81.3%, ceftazidime 79.0%, piperacillin-tazobactam 78.3%, imipenem 77.1%, ampicillin-sulbactam 75.6%, gentamicin 68.8%, ceftriaxone 68.7%, tobramycin 62.1%, cefoperazone-sulbactam60.5%, levofloxacin 58.7%, cotrimoxazole 57.5%, minocycline 55.5%.Conclusion:Acquried infection rate within the hospital of A.calcoaceticus-A.baumannii composite increases every year, and isolated A.calcoaceticus-A.baumannii composite show drug resistance to a variety of antimicrobial. Resistance monitoring of A.calcoaceticus-A.baumannii composite should be strengthened,antibiotics should be used rational, regional hospitals combined detection mechanism should be established , broad resistance trends of A.calcoaceticus-A.baumannii composite should be grasped.
查看全文  查看/发表评论  下载PDF阅读器
关闭